产品货号：
Z26150
中文名称：
SIL/STIL抗体
英文名称：
Anti-SIL/STIL Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SIL/STIL Antibody |
| 指标别名 | STIL;SIL;SCL-interrupting locus protein;TAL-1-interrupting locus protein |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,FCM,ELISA |
| 基因名称 | STIL |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human STIL/SIL recombinant protein (Position:N13-F1287). |
| 实际分子量 | 170KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | SCL-interrupting locus protein is a protein that in humans is encoded by the STIL gene.This gene encodes a cytoplasmic protein implicated in regulation of the mitotic spindle checkpoint,a regulatory pathway that monitors chromosome segregation during cell division to ensure the proper distribution of chromosomes to daughter cells.The protein is phosphorylated in mitosis and in response to activation of the spindle checkpoint,and disappears when cells transition to G1 phase.It interacts with a mitotic regulator,and its expression is required to efficiently activate the spindle checkpoint.It is proposed to regulate Cdc2 kinase activity during spindle checkpoint arrest.Chromosomal deletions that fuse this gene and the adjacent locus commonly occur in T cell leukemias,and are thought to arise through illegitimate V-(D)-J recombination events.Multiple transcript variants encoding different isoforms have been found for this gene. |
| Uniprot ID | Q15468 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | STIL centriolar assembly protein |
| 蛋白名全称 | SCL-interrupting locus protein |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section IHC 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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